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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1abd819149dc1df3234a62bd77b11c6f7c6af52aac7b6f2da02d2f3e494ddd27' 
  AND token = 'aac8fVS1NkGCF1ovfYb3YDhHr6YxlIcDGh0pqKwAQ6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}