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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bfc50a8214a7aee1bbcc3b3dda3f456cbeec3a74cab9ecb624adbeec4aa3e55' 
  AND token = '46T03KuyWse5Q45b59g5hu6qZwe18BSnqoW0RlchiG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}