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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b17e14c36f88bd5e6c0fdb708552a38b35979ec35efe4d9125817fc741a78c20' 
  AND token = 'bqCdmu+aUMaCqoQmUFT8lqCf/NxfYqeDBn7X8uuqerE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}