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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ac4298815b89f5fee107482ebc576a3ad46dbbf48cc3f2c62911955a0f7186' 
  AND token = '6wxddyU+lW1LHB3HTz7kMTmfaIAT2r+4uiqkdDMZ46g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}