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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de47d6a52605b09693fc7f356371202671fbb60943526b7f507d9a4fcf4e0b9c' 
  AND token = 'iEqar7q1V+E+TUOUOlXWCX/aoP6g8Dky5EXfeLsaC2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}