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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d105fe813b2d911ae2392a38c605c75e5e4e96601be8c608358c57abc315b5' 
  AND token = 'pfuLghp3kFfVP9d3hQ/M8xXfOx0fTaFwQ5mHY3aKyuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}