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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd394ce04bf64cda7b1aa3d1fa87dfca04aea595c396ace7170da96a2d5f36c25' 
  AND token = 'phB4kw06NDXI3GCj/LN878YQedgi60g4zSP3e/Cy4/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}