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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd5c42716e484a261c2acde38e7b4cdbb50e64e31cc8086a1bc9e0e7b8ceb2e' 
  AND token = 'UTA2LrbtuihvzUf/hmIHLcf9PGj0cmrWUQj24RyrUQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}