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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048b0dfaece7c43b080b7e8e80cf8a022f26041be8a67d4e91d63802611cf168' 
  AND token = '7TGxQoPav5ho7ByghwkjijSa4lK0mXnpFfkAYUtUMuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}