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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c260c34e8d536cffb793a97ba7e7adc3d39affff45b9cd4412db54f7a2ccdb3' 
  AND token = 'y6m3z/QpSIX/mreW4s/HSIdo5cvZRxkSuMM/pIiKsHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}