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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44af71fd6a4c5c109ee563c0408c10f9ab50d32ce5821207486c3d7c9d5ac5eb' 
  AND token = 'ecah4JLVycgk2/cIG5WotxOPsFrzgjNBpEYbHyLmpeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}