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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0c6fd1b9f7b6ed56ab4d9574611e3ff4a114f335fa7af61e0e4c84e4423115' 
  AND token = 'bo16+CYtn8GEZv9fhM3CvicAHxK5ZFTYf3ovWQlp7Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}