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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '275e34ec85e90b4091d62264267e8355feaf30eee58a366f2e5cad68fd9c30f3' 
  AND token = 'nuDSpZF3nmFs6F5SQIJEwRd6JYhU/KmtJXqBOuJ2BJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}