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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b73a1a8cc4e95d49ff20ec4b9cd5e25f41c408f3d5a02d45206412606d7813f7' 
  AND token = 'IDiwKqXo8QQ2U+rik4m8c1uEtdARmaHUwODkEqgobwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}