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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4508700ba0d5ffdcd81f60ccec09e238ec50e57ebecea4e59b7a6f0fbfb45daf' 
  AND token = 'Z9WttQJZlY82ivdXIN9swCfcGDmpDTNerE05Cf9bUpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}