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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a67d35580e865cc8ec7e8c7d8664b35d5b2f050641f213d80c0d74117e6689fe' 
  AND token = 'sQ7265jGFdQ15mir0GaG+V/DbRC8tGEeZuuVCDiqV/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}