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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a45f199cb1b3eeb9d533731a4028995f5787b86b004856d05e72efa66f7696b' 
  AND token = 'pBBIMxf+k1Rsp/3SeD06Lgyih4gyZ4cfU8JgYgZJagI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}