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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b466c458b8ea76ab2d9b51d28364d693b09e83bd40d3fb93d84567c1c98edff5' 
  AND token = 'ZXvbgySTdrUjSFKxoI3b/DVZ3sDK2X2ppprAgm27U7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}