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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e7b28cc66ab332c4cdd71e23bb2ecaddb1b7d0c4e717a5afe57a54e45b25e03' 
  AND token = 'eDAXmjGrsq9u45+rSyGdL3CgdyXgBlKozESq20htBZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}