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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bde3899d7010cb122e3b5eef4e2ad6f63c34f81dd7c50e3b31241bfa13603859' 
  AND token = 'Zw62WT1RIBxd7wYhonAioR6AcW5wa80nUGciJvccTqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}