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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b55864733486de9263ba8647b2d398a7180c03e0f8c8dcf3889a65517710e4' 
  AND token = '9BxSJ3tC1teJll079QxzLMEqQeQaxajiPyO6RuqIzfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}