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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d30a4147ac46587a44017200f0b4ef0704ab0a559543e90454639000a93f015' 
  AND token = 'Y3Ov+xU95CRqQR/2TSCnaIsskVhgObdm5dL/gH28Zao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}