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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75164ec74609983137deb72162a6fe178c4e33f194a21b29e57c13c78507d347' 
  AND token = 'ndIn+u2B12S8axjGq2+6JzR45x3lWYP/iaS7S01hJ94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}