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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0876f340b99a227d1cf2d08bd614c8d3504e66cab2aeee1b4f63b822e3339af7' 
  AND token = 'RLsocjlBZ0jlw9c1ErHfgJU955Rtwp0dFTcmEHrs7XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}