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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9ce097c88dd884516bbbd592a0f0f144bb3a435bf9e756faa550e9cf217b726' 
  AND token = 'vk7zMnhvA8wr7F0xEbjmZAzpp5dP9QAlF9Ofi2ur5FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}