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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e950af992353e98fdde9621ca075ad16e42fa8de49185e1fe27056b0a6800a8a' 
  AND token = 'c2Z0HZpH412fm+aEEc0ujo7WsV+3qW+p0ONKXuyVh9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}