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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dbe721c88171c6cca4da57e776f56c56aa3936fb2ac421fb9baafc0864458c5' 
  AND token = 'zlY0tf64O2SOtv5yxEnQoACVCFQmYBYKiGH4rWZRtkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}