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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c00a716978f7c1138a63a7092af72f07a5f3547e121bcf294b801f7930835c15' 
  AND token = 'aTBafKXJsh3l9VhzVSdLpCd2jsOzREmExaSo3NxgOPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}