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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3638f44134d97cb027160f0f800fad7f8fc8b0a5b309b115f9fae7444631cd3' 
  AND token = 'O46imthfNrK8zwSoE1aBWhcmbaTarh1vWVPZesE4jfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}