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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c617b24340455182074969d4a832e92aff2cf1ae265a1f237d408a4fa123df0' 
  AND token = '9Unf/O0dZsb1q+QpkRGBXK00I2ZVQVLx4pUcfGF9kdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}