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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4423dfa4ae59f7ba46bcd4505525e94d5c76da336d3ed13d243a69286fce5cf1' 
  AND token = 'XExIPBON6AlvPta6r0I2NFoC/EQ7mwEUcBp7FwBwL9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}