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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d7e5a0512f5a3f31f231b684763965545c9b74a37b3810c1ed826b467feb50' 
  AND token = 'SGb4xFAIqO4vjyvt7zTqR1QsRk3NGZqm7vs0OKbIOsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}