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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '350de38aaffa240b15bfae5e2777aade6d1d1a653d4869963cd648fa681a75e0' 
  AND token = 'jdUSUnv0a+QxN6yS9ggGdPdNbP9YCzFMtmptZ3YpkRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}