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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c67601b5fd1e52b99371429d4bd5c1f196c7a511819b10a0d481cf0035babff' 
  AND token = 'i/EsfRybYBKQThL5qBkMi9rqVXLVfT9udW8r38h4tCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}