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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '282c6a6c704e2e52a885d7c6b424e41910928b7e86dd17802ec58251e9ae6935' 
  AND token = '5r+d8rG0oOhLItkzJBO4zHJPu+isE/1ucaCRXL9FnEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}