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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df0b9b1a68059efc8dee43fc80e132b4c23fac85816769e55acf2e0240fae8dd' 
  AND token = 'fhUx9NvYAv5czMm8y9EBw+y5Uea1fHrndlUPp60N0DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}