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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '095ac0b78adbce270648a01c3d0dcc2ad187fa4220e776fb76156a86670fd921' 
  AND token = 'elSMPVlrCJL2hy1ilA125ahXJ0A9eb5wTRWXLbSdUV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}