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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '476f76d4dd51d71922b5bac3504ff7183eb70c31a8c6b28575a09ad1375e1752' 
  AND token = 'T2VrKNzKmDm+h7Uh6QIje4uiT0iP3iySCC9v2bbVhGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}