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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463af3cfc6983fb230de2112b8d10c88f0b75bd7e65edc277eb1646674baeb54' 
  AND token = 'UzKf/39RKKxAxVowS8dRdcc9JyN6LGCo8RDM4P3sGbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}