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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '319f505c1e1a749a038ada1b3a900b409a1d7e85c001d543c5121aeac93dcecf' 
  AND token = 'NCsNTVHCpKU060Aj7O5i40P8UrjuFjl3Y7hRKffEixQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}