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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d18e52bedbcf7b08eb28b7608c516ae8882bfb349297f5cc9a5c57d65f874a4' 
  AND token = 'RYmlTKS7RZskuB8SNj5rLEO0v+sXGBXAWcocu21UboY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}