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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '586ee8b1f07fcb7b37a70869540e4b0c61c01a516ab3a3530c86006282ce54d9' 
  AND token = 'Ht4tZeT+u9jN4OaRvl5Y1lB6JK9BjNPPNzD4xr3zmHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}