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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6eedb465bca03e03a11b3a3f5345a04f672914082c967ad28bd6f5fd0aaf8c5' 
  AND token = 'kifOGdxck836rKcV2hDnMPHaXM1FgkS+lrh4Xb7YQF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}