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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e514c3b7daa536519c751a06b2109011e5b2acdde6222a36bf2363b7de2a149f' 
  AND token = 'poFawbeItrSdUVy86EgDdlZPSx9pOig0ixUejcH1MuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}