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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45066a5ac6ae2937a5f618c8e9668b5608da56ce511de1867532039becd69f56' 
  AND token = 'pX/tv0iUc5gtC6wyHDQKUWukQH1IYihMAJwAf/3dWjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}