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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64220a0caea5a912edfa63a7d8b1768ef304c894eef4f9495ad8118801ea9c76' 
  AND token = 'nYtqdU5WAv/NvPsYKZw5XvYaVnvrlFIga2tNNRs4D6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}