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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80867e329feea9abad8f0c7399b1fb1b65ca1de4d42754292fb39bf35b8bd556' 
  AND token = 'LK0OY5e6jCnPOtNxiVu4SrR3pZ3XfxLyng7mtURzOsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}