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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9507809dc8cbf9a91b99268c40ee2f6b5a86fd93f087a675f3c5bae2e2e7c280' 
  AND token = 'P0oVZ03czP6HzNypT/z47ErlfYubUItHlql6rmXr6Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}