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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5000bccd8d54a2ed32b57c9bbef029cb5b448dee5c3ce57f2b3e01ef731572e8' 
  AND token = 'DXovnWSC6qWq7vKAKxLIigGAFy/HYgME80+8che21zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}