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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3714dc953c80f655807b21e2e9278cfada3576272fd0dc61011fb8074c3b8d16' 
  AND token = 'vO3oREAOQo2tOTISeV8bpNE2H81DpytrJpNFktWFMgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}